Alcohol consumption and kidney function decline in the elderly: Alcohol and Kidney Disease.
Nephrol Dial Transplant. 2010 Apr 15.
Menon V,
Division of Nephrology, Tufts Medical Center, Boston, USA.
Abstract
BACKGROUND: Alcohol consumption appears to be protective for cardiovascular disease; however, its relationship with kidney disease is unclear.
METHODS: This prospective cohort study included 4343 subjects from the Cardiovascular Health Study, a longitudinal, community-based cohort of persons aged >/=65 from four US communities. We used previously defined categories based on weekly alcohol consumption: none, former, <1 drink, 1-6 drinks, 7-13 drinks and >/=14 drinks. Cystatin C was measured at baseline, year 3 and year 7; eligible subjects had at least two measures. Estimated GFR(cys) was calculated from cystatin C. The primary outcome was rapid kidney function as an annual estimated GFR (eGFR(cys)) loss >3 mL/min/1.73 m(2)/year.
RESULTS: Eight percent of the cohort reported former alcohol use and 52% reported current alcohol consumption. During a mean follow-up of 5.6 years, 1075 (25%) participants had rapid kidney function decline. In adjusted logistic regression models, there was no association between alcohol use and kidney function decline (odds ratio, 95% confidence interval: none = reference; former = 1.18, 0.89-1.56; <1 drink = 1.20, 0.99-1.47; 1-6 = 1.18, 0.95-1.45; 7-13 = 1.10, 0.80-1.53; >14 = 0.89, 0.61-1.13). Results were similar with kidney function decline as a continuous outcome.
CONCLUSIONS: Our results suggest that moderate alcohol consumption has neither adverse nor beneficial effects on kidney function. Although clinicians will need to consider the potential deleterious effects associated with alcohol consumption, there does not appear to be a basis for recommending that older adults discontinue or initiate light to moderate alcohol consumption to protect against kidney disease.
New Feature from Hemodialysis.com: Hemodialysis or Chronic Kidney Disease Abstract of the Week
Zasuwa G, Frinak S, Besarab A, Peterson E, Yee J.
Division of Nephrology and Hypertension, Department of Internal Medicine, Henry Ford Hospital, Detroit, Michigan.
Although monitoring of vascular accesses by physical examination is nearly as sensitive as surveillance measurements by vascular access pressure when performed by examiners, the frequency of examinations is limited by time.
We developed intravascular access pressure surveillance as a surrogate to physical examination. Using real-time data from hemodialysis machines, we derived intravascular access pressure ratios for each dialytic procedure. An automated, noninvasive surveillance algorithm that generated a "warning" list of patients at risk for thrombosis was formulated.
We hypothesized that this algorithm would reduce access thrombosis frequency. We designed a study comparing thrombosis rates during a baseline 6-month interval to three subsequent 6-month periods of active surveillance.
Referrals for interventions during this 18-month period were based on persistently abnormal elevated vascular access pressure ratio tests (VAPRT) >0.55.
Thrombosis rates declined progressively for arteriovenous grafts (AVG) during the intervention period compared with the baseline period.
Arteriovenous fistula (AVF) thrombosis rates decreased during postintervention months 13-18 during employment of the VAPRT.
We conclude that use of VAPRT can reduce thrombosis rates in vascular accesses, and the magnitude of the effect is larger and more consistent in arteriovenous grafts (AVGs) than autologous AVFs.
Hemodialysis | Kidney Disease | Dialysis Resources and Educational Materials
100 Q&A About Kidney Disease and Hypertension
Raymond R. Townsend, MD
High blood pressure is one of the leading causes of kidney failure. Each year, high blood pressure causes more than 25,000 new cases of kidney failure in the United States. 100 Questions & Answers About Kidney Disease and Hypertension offers authoritative, up-to-date, practical answers about kidney disease, end-stage renal disease, transplants, and dialysis. The book is an invaluable resource for anyone coping with the physical and emotional turmoil of this condition.
Handbook of Dialysis Therapy
Here's an in-depth, quick-reference, problem-solving resource for those involved in the care of dialysis patients. More than 120 world-class authorities discuss dialysis techniques, mechanical considerations, and complications related to various diseases for both pediatric and adult patients. Selected annotated references and excellent cross-referencing between chapters help you find answers fast, and more than 100 photos, drawings, charts, and tables, mostly in color, clarify complex topics. Providing practical, immediately useful guidelines that can be applied directly to patient care, this book is a "must-have" for all dialysis caregivers.
Certified Hemodialysis Technologist/Technician Exam Secrets Study Guide: CHT Test Review for the Certified Hemodialysis Technologist/Technician Exam
Certified Hemodialysis Technologist/Technician Exam Secrets helps you ace the Certified Hemodialysis Technologist/Technician Exam, without weeks and months of endless studying. Our comprehensive Certified Hemodialysis Technologist/Technician Exam Secrets study guide is written by our exam experts.....
Dialysis and Hemodialysis Book and Descriptions from Amazon.com
Please visit the Hemodialysis.com Google Ad Sponsors
The information on Hemodialysis is for informational purposes only and is not intended as specific medical advice or to be a substitute for medical advice from your physician or health care provider. Please check with a physician if you need a diagnosis and/or for treatments as well as information regarding your specific condition.
Please read Medical Disclaimer as term of condition for usage of this website.
If you are experiencing urgent medical conditions, call 9-1-1
Copyright 2010 EminentDomains.com®. All Rights Reserved.
Our Success is Linked to Your Success®
