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Diabetes is a leading cause of kidney failure leading to CKD (chronic kidney disease) and kidney failure, that may necessitate Dialysis or Hemodialysis. Diabetes is an increasing problem in the United States, often associated with the growing obesity epidemic.
Hemodialysis.com presents ongoing research articles into diabetes research and management and the implications for chronic kidney disease.
Diabetes | Dialysis | Hemodialysis
| Chronic Kidney Disease
Updated October 31 2012
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Hemodialysis.com Author Interview: Dr. Robert Nelson, MD, PhD
Associations of kidney disease measures with mortality and ESRD in individuals with and without diabetes: a meta-analysis
Caroline S Fox MD,Kunihiro Matsushita MD,Prof Mark Woodward PhD,Prof Henk JG Bilo MD,Prof John Chalmers MD,Hiddo J Lambers Heerspink PharmD,Brian J Lee MD,Robert M Perkins MD,Prof Peter Rossing MD,Toshimi Sairenchi PhD,Prof Marcello Tonelli MD,Joseph A Vassalotti MD,Kazumasa Yamagishi MD,Prof Josef Coresh MD,Prof Paul E de Jong MD,Chi-Pang Wen MD,Robert G Nelson MD,for the Chronic Kidney Disease Prognosis Consortium
The Lancet - 24 September 2012
DOI: 10.1016/S0140-6736(12)61350-6
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Hemoglobin A1c Levels and Mortality in the Diabetic Hemodialysis Population: Findings from the Dialysis Outcomes and Practice Patterns Study (DOPPS).
Ramirez SP, McCullough KP, Thumma JR, Nelson RG, Morgenstern H, Gillespie BW, Inaba M, Jacobson SH, Vanholder R, Pisoni RL, Port FK, Robinson BM.
Arbor Research Collaborative for Health, Ann Arbor, Michigan.
Diabetes Care. 2012 Aug 21. [Epub ahead of print]
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Frank-Peter Tillmann, Ivo Quack, Ana Schenk, Bernd Grabensee, Lars C. Rump,and Gerd R. Hetzel
Nephrol. Dial. Transplant. first published online April 6, 2012 doi:10.1093/ndt/gfs020
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Dart AB, Sellers EA, Martens PJ, Rigatto C, Brownell MD, Dean HJ.
Diabetes Care. 2012 Mar 19. [Epub ahead of print]
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Helen Vlassara, Jaime Uribarri, Weijing Cai, Susan Goodman, Renata Pyzik,James Post, Fabrizio Grosjean, Mark Woodward, and Gary E. Striker
CJASN CJN.12891211; published ahead of print March 29, 2012,doi:10.2215/CJN.12891211
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Hien Pham, Cassianne Robinson-Cohen, Mary L. Biggs, Joachim H. Ix,Kenneth J. Mukamal,
Linda F. Fried, Bryan Kestenbaum, David S. Siscovick, and Ian H. de Boer
CJASN CJN.11861111; published ahead of print March 1, 2012,doi:10.2215/CJN.11861111
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NKF: Protect Your Kidneys, Prevent Pre-Diabetes
Kidneys play a life sustaining role in the body. Healthy kidneys filter your blood, regulate blood pressure and remove waste products and excess fluid from the body. During March, National Kidney Month, the National Kidney Foundation (NKF) is sounding the alert about a little-known condition called prediabetes that can damage the kidneys. According to the NKF, the good news is that prediabetes is reversible if detected early. |
Early Basal Insulin Therapy Decreases New-Onset Diabetes after Renal Transplantation
Manfred Hecking, Michael Haidinger, Dominik Döller, Johannes Werzowa, Andrea Tura,Jinyao Zhang, Hilal Tekoglu, Johannes Pleiner, Thomas Wrba,Susanne Rasoul-Rockenschaub, Ferdinand Mühlbacher, Sabine Schmaldienst,Wilfred Druml, Walter H. Hörl, Michael Krebs, Michael Wolzt, Giovanni Pacini, Friedrich K. Port, and Marcus D. Säemann
JASN Feb 16, 2012 ASN.2011080835; published ahead of print February 16, 2012,doi:10.1681/ASN.2011080835
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Author Interview: Tomonari Ogawa, M.D. Ph.D
Ogawa, T., Murakawa, M., Matsuda, A., Kanozawa, K., Kato, H., Hasegawa, H. and Mitarai, T. (2011),Hemodialysis International. doi: 10.1111/j.1542-4758.2011.00640.x
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ASN 2011 Abstract Authors' Interview:
Hypoglycemia-Related Hospitalization in Diabetic Hemodialysis Patients.
Eduardo Lacson, Jr., MD, MPH, Weiling Wang, MS, Michael Lazarus, MD, Mark Williams, MD
Fresenius Medical Care, Waltham, MA, and Joslin Diabetes Center, Boston, MA
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Author Interview: Sirin Jiwakanon, MD.
Change in Ankle-Brachial Indices over Time and Mortality in Diabetics with Proteinuria
ASN 2011 Abstract:
Sirin Jiwakanon, MD, Sharon G. Adler, MD, FASN, Rajnish Mehrotra, MD, FASN. Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA, Torrance, CA; Medicine, Hatyai Hospital, Hatyai, Songkhla, Thailand.
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Author Interview: Dr. Timothy Kenealy
Timothy Kenealy, Carolyn Raina Elley, John F. Collins, Simon A. Moyes,
Patricia A. Metcalf, and Paul L. Drury Nephrol. Dial. Transplant.
(2011)first published online September 13, 2011 doi:10.1093/ndt/gfr540
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Fresenius Medical Care Will Be a Speaker Sponsor at the American Diabetes Association's EXPO Pittsburgh
Company to Host Educational Seminars to Promote Awareness of Kidney Disease for the At-Risk Community
PITTSBURGH – November 1, 2011 – Diabetes is the single leading cause of kidney failure in the U.S., accounting for about 44 percent of the people who start treatment for kidney failure each year. To help raise awareness of the links between diabetes and chronic kidney disease (CKD), Fresenius Medical Care North America (FMCNA), the nation’s leading network of dialysis facilities, will be a speaker sponsor at the American Diabetes Association (the Association) EXPO Pittsburgh, to be held at the David L. Lawrence Convention Center, on Saturday, Nov. 5, from 9:00 a.m. – 4:00 p.m.
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Author Interview: Matthew Budoff, MD
Relationship of Estimated GFR and Coronary Artery Calcification in the CRIC (Chronic Renal Insufficiency Cohort) Study.
Budoff MJ, Rader DJ, Reilly MP, Mohler ER 3rd, Lash J, Yang W, Rosen L, Glenn M, Teal V, Feldman HI; CRIC Study Investigators.Los Angeles Biomedical Research Institute at Harbor-UCLA, Torrance, CA.
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Holdaas H, Holme I, Schmieder RE, Jardine AG, Zannad F, Norby GE, Fellström BC; on behalf of the AURORA study group.
J Am Soc Nephrol. 2011 Jul;22(7):1335-1341
Renal Section, Oslo University Hospital, Rikshospitalet, Oslo, Sognsvannsveien 22, 0072 Oslo, Norway
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Author Interview: Barry I. Freedman, M.D.
Glycated Albumin and Risk of Death and Hospitalizations in Diabetic Dialysis Patients.
Freedman BI, Andries L, Shihabi ZK, Rocco MV, Byers JR, Cardona CY, Pickard MA, Henderson DL, Sadler MV, Courchene LM, Jordan JR, Balderston SS, Graham AD, Mauck VL, Russell GB, Bleyer AJ.
Clin J Am Soc Nephrol. 2011 May 19 |
Author Interview: Dr. Hallvard Holdaas:
Rosuvastatin in Diabetic Hemodialysis Patients.
Am Soc Nephrol. 2011 May 12.
Holdaas H, Holme I, Schmieder RE, Jardine AG, Zannad F, Norby GE, Fellström BC; on behalf of the AURORA study group.
Department of Nephrology, Oslo University Hospital, Rikshospitalet, Oslo, Norway; |
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Centers for Disease Control and Prevention (CDC).
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Am J Med Sci. 2010 Oct 4.
Obert DM, Hua P, Pilkerton ME, Feng W, Jaimes EA.
From the Division of Nephrology (dmo, ph, mep, wf, eaj), Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama; and VA Medical Center (eaj), Birmingham, Alabama. |
| Erythropoietic Response and Outcomes in Kidney Disease and Type 2 Diabetes
N Engl J Med 2010; 363:1146-1155 September 16 2010 Scott D. Solomon, M.D., Hajime Uno, Ph.D., Eldrin F. Lewis, M.D., M.P.H., Kai-Uwe Eckardt, M.D., Julie Lin, M.D., M.P.H., Emmanuel A. Burdmann, M.D., Ph.D., Dick de Zeeuw, M.D., Ph.D., Peter Ivanovich, M.D., Andrew S. Levey, M.D., Patrick Parfrey, M.D., Giuseppe Remuzzi, M.D., Ajay K. Singh, M.D., Robert Toto, M.D., Fannie Huang, M.S., Jerome Rossert, M.D., Ph.D., John J.V. McMurray, M.D., and Marc A. Pfeffer, M.D., Ph.D. for the Trial to Reduce Cardiovascular Events with Aranesp Therapy (TREAT) Investigators |
J Ren Nutr. 2010 Sep;20(5 Suppl):S89-94. Ngo B, Rongey C, Hiscox B, Rendell M, Woodley D, Smogorzewski M.
Department of Dermatology, University of Southern California, Keck School of Medicine, Los Angeles, California, USA. |
Clin J Am Soc Nephrol. 2010 Jul 29.
Williams ME et al
Joslin Diabetes Center, Boston, Massachusetts et al
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Clin J Am Soc Nephrol. 2010 Jul 29.
Ix JH. |
The heart and diabetic nephropathy.
Methodist Debakey Cardiovasc J. 2010 Apr-Jun;6(2):9-14.
Olivero JJ Jr.
Methodists DeBakey Heart & Vascular Center, Houston, Texas. |
Int Urol Nephrol. 2010 Jul 24. Israel E, et al
Department of Internal Medicine, Nephrology Division, Staten Island University Hospital, 475 Seaview Avenue, Staten Island, NY, USA. |
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Curr Diab Rep. 2010 Jun 8.
Ndip A, et al |
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Semin Dial. 2010 Mar;23(2):191-7.
Passadakis PS, Oreopoulos DG. |
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This study explored factors in childhood that may help pediatricians and physicians predict the risk of diabetes later in adulthood.
Risk factors included:
Elevated Body Mass Index (BMI)
Elevated blood pressure
Parental diabetes
Laboratory changes: Glucose, Lipids, Insulin
The authors used a combination of these factors in childhood to predict later onset of Type II diabetes.
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Cerebral Microvascular Disease Predicts Renal Failure in Type 2 Diabetes -- Abstract
Takashi Uzu et al
Shiga University of Medical Science, Otsu, Shiga, Japan et al
Journal of the American Society of Nephrology
American Society of Nephrology
doi: 10.1681/ASN.2009050558 |
This study evaluated patients with Type 2 Diabetes for evidence of silent cerbral vascular injury by using MRI imaging. The authors report an increased risk of development of end stage renal disease in patients with abnormal, silent findings of cerebral vascular disease and concluded:
"independent of microalbuminuria, cerebral microvascular disease predicted renal morbidity among patients with type 2 diabetes.". |
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