Infections In Patients with Kidney Disease -
Dialysis - Hemodialysis - ESRD

 
Infections in Hemodialysis Dialysis End Stage Renal Failure Patients
Updated Dec 20 2012

Hemodialysis.com Author Interview: Shree G Sharma, M.D.

BK polyoma virus nephropathy in the native kidney

Shree G. Sharma, Volker Nickeleit, Leal C. Herlitz, Anne K. de Gonzalez, Michael B. Stokes, Harsharan K. Singh, Glen S. Markowitz, and Vivette D. D'Agati

Nephrol. Dial. Transplant. first published online December 18, 2012 doi:10.1093/ndt/gfs537

Hemodialysis.com Author Interview: Akiko Kowada, MD, PhD

Cost effectiveness of the interferon-γ release assay for tuberculosis screening of hemodialysis patients

Akiko Kowad Nephrol. Dial. Transplant. first published online December 13, 2012 doi:10.1093/ndt/gfs479

Hemodialysis.com Authors' Interview Thomas Rogerson and Angela Webster

Tests for latent tuberculosis in people with end stage kidney disease: a systematic review.
Rogerson T, Chen S, Kok J, Hayen A, Craig JC, Kable K, Sud K, Webster AC.
American Journal of Kidney Diseases 20122012 Oct 13. pii: S0272-6386(12)01060-8. doi: 10.1053/j.ajkd.2012.07.01

Hemodialysis.com Author : Macaulay Onuigbo MD MSc FWACP FASN MBA

De novo HBV infection in a Mayo Clinic hemodialysis population: Economic impact of reduced HBV testing and a call for changes in current US CDC guidelines on HBV testing protocols.

Onuigbo, M. A. C. and Onuigbo, N. T. C. (2012)
Hemodialysis International, 16: S32–S38. doi: 10.1111/j.1542-4758.2012.00748.x

Hemodialysis.com Author Interview: Shih-Yi Lin

Association of response to hepatitis B vaccination and survival in dialysis patients
lin S, liu J, Wang S, Wang I, Tsai C, Liu Y, Lin H, Chang C, Huang C
BMC Nephrology 2012, 13:97 (30 August 2012)

Hemodialysis.com Author Interview: Dr. Chin-Chun Shu

Predictors and prevalence of latent tuberculosis infection in patients receiving long-term hemodialysis and peritoneal dialysis

Shu C-C, Wu V-C, Yang F-J, Pan S-C, Lai T-S, et al. (2012)PLoS ONE 7(8): e42592. doi:10.1371/journal.pone.0042592

Hemodialysis.com Author Interview: Chukwuma Mbaeyi BDS (DDS), MPH

Assessment of Management Policies and Practices for Occupational Exposure to Bloodborne Pathogens in Dialysis Facilities

Mbaeyi C, Panlilio AL, Hobbs C, Patel PR, Kuhar DT.
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA; Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA.
Am J Kidney Dis. 2012 Jun 26. [Epub ahead of print]

Hemodialysis.com Author Interview: Gagangeet Sandhu MD

Effect of Aggressively Driven Intravenous Iron Therapy on Infectious Complications in End-Stage Renal Disease Patients on Maintenance Hemodialysis

Bansal, Anip MD; Sandhu, Gagangeet MD; Gupta, Isha MD; Kalahalli, Shriharsha MD; Nayak, Rushi MD; Zouain, Eduardo MD; Chitale, Rohit A PhD, MPH; Meisels, Ira MD; Chan, Germaine MD

POST AUTHOR CORRECTIONS, 23 July 2012
doi: 10.1097/MJT.0b013e31825425bd

Author Interview Dr. AM Onder

Antibiotic lock solutions allow less systemic antibiotic exposure and less catheter malfunction without adversely affecting antimicrobial resistance patterns.

Onder, A. M., Billings, A. A., Chandar, J., Nield, L., Francoeur, D., Simon, N., Abitbol, C. and Zilleruelo, G. (2012), Hemodialysis International. doi: 10.1111/j.1542-4758.2012.00717.x

Risk factors and outcome of contamination in patients on peritoneal dialysis 

Desmond Y. Yap, Wai Ling Chu, Flora Ng, Terence P. Yip,  Sing L. Lui, and Wai K. Lo

Perit Dial Int pdi.2011.00268; published ahead of print June 1, 2012
doi:10.3747/pdi.2011.00268

Risk of Herpes Zoster in CKD:
A Matched-Cohort Study Based on Administrative Data

Am J Kidney Dis. 2012 May 8. [Epub ahead of print]

Wu MY, Hsu YH, Su CL, Lin YF, Lin HW.

Department of Nephrology, Shuang Ho Hospital, 
Taipei Medical University, Taipei, Taiwan.

Author Interview: Sarah Yi, PhD

Reduction in Bloodstream Infection Rates in Outpatient Hemodialysis Centers Participating in a CDC Prevention Collaborative

Authors: Sarah H. Yi, Alexander J. Kallen, John A. Jernigan, Priti R. Patel
for the members of the CDC Dialysis BSI Prevention Collaborative
Affiliation: Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention (CDC), Atlanta, GA USA
Presented at National Kidney Foundation Spring Clinical Meeting 2012

Author Interview: John J. Dixon MD

Anti-microbial locks increase the incidence of Staphylococcus aureus and antibiotic-resistant Enterobacter:
observational retrospective cohort study

John J. Dixon, Maggi Steele and A. David Makanjuola
Nephrol. Dial. Transplant. first published online April 18, 2012 doi:10.1093/ndt/gfs081

Author Interview: Carlos Jorge da Silva, MD
Efficacy of preventing hemodialysis catheter infections with citrate lock.


Silva J, Antunes J, Carvalho T, Ponce P.
Hemodial Int. 2012 Apr 20. doi: 10.1111/j.1542-4758.2012.00691.x.
[Epub ahead of print]
Department of Hemodialysis, Nephrocare Grândola, Grândola, Portugal.

Authors' Interview:
M. Alan Brookhart, PhD and Leah McGrath, MHS

Influenza Vaccine Effectiveness in Patients on Hemodialysis
An Analysis of a Natural Experiment

Leah J. McGrath, MHS; Abhijit V. Kshirsagar, MD, MPH; Stephen R. Cole, PhD; Lily Wang, PhD;David J. Weber, MD, MPH; Til Stürmer, MD, MPH; M. Alan Brookhart, PhD 
Arch Intern Med. 2012;172(7):548-554. doi:10.1001/archinternmed.2011.2238

Dynavax: HEPLISAV, a Phase 3 Data on investigational adult Hep B vaccine, update in CKD and Hemodialysis Patients

BERKELEY, CA, Mar 27, 2012 (MARKETWIRE via COMTEX) -- Dynavax Technologies Corporation today announced final data from a pivotal Phase 3 trial in patients with chronic kidney disease (CKD) demonstrating early seroprotection and the durability of the immune response to HEPLISAV compared to Engerix-B(R). In October 2011, Dynavax reported that the superiority endpoint had been met in this trial. The trial included 516 patients 18-75 years of age with CKD (stage 3b or higher) in the U.S., Canada and Germany who received 3 doses of HEPLISAV at 0, 1 and 6 months or 4 double doses of Engerix-B at 0, 1, 2 and 6 months (8 doses total).

Reducing Bloodstream Infections in an Outpatient Hemodialysis Center — New Jersey, 2008–201

Morbidity and Mortality Weekly Report (MMWR) Source: http://www.cdc.gov/mmwr/pdf/wk/mm6110.pdf

Download the full PDF including tables

March 16, 2012 / 61(10);169-173

Patients undergoing hemodialysis are at risk for bloodstream infections (BSIs), and preventing these infections in this high-risk population is a national priority (1). During 2008, an estimated 37,000 BSIs related to central lines occurred among hemodialysis patients in the United States. This is almost as many as the estimated 41,000 central line–associated BSIs that occurred during 2009 among patients in critical-care units and wards of acute-care hospitals. In 2009, to decrease BSI incidence in a New Jersey outpatient hemodialysis center, a package of interventions was instituted, beginning with participation in a national collaborative BSI prevention program and augmented by a social and behavioral change process to enlist staff members in infection prevention.

Rates of BSIs related to the patient's vascular access (i.e., access-related BSIs [ARBs]) were evaluated in the preintervention and postintervention periods. The incidence of all ARBs decreased from 2.04 per 100 patient-months preintervention to 0.75 (p=0.03) after initiating program interventions and to 0.24 (p<0.01) after adding a behavioral change intervention. Only one ARB occurred during the last 12 postintervention months. At this hemodialysis facility, participating in a collaborative prevention program along with implementation of a behavioral change strategy was associated with a large decrease in ARBs. Other outpatient hemodialysis facilities also might reduce ARBs by adopting similar approaches to prevention.

ASN 2011 Abstract Authors' Interview:

Outcomes from a Multi-Center Catheter Reduction Collaborative Program.

Alex Rosenblum, RN, CNN, Eduardo Lacson, Jr., MD, MPH, Jill Hall, RN, CNN, Shu-Fang Lin, MA, Raymond Hakim, MD, PhD. Fresenius Medical Care, Waltham, MA.

Author Interview: Dr. Sarbjit Vanita Jassal
A Randomized Controlled Trial Comparing Mupirocin and Polysporin Triple Ointments in Peritoneal Dialysis Patients: The MP3 Study


McQuillan RF, Chiu E, Nessim S, Lok CE, Roscoe JM, Tam P, Jassal SV.
University Health Network, Toronto, Canada;
Clin J Am Soc Nephrol. 2011 Dec 1.
Author Interview: Dr. Mira T Keddis MD

Clinical Outcomes of Clostridium difficile Infection in Patients with Chronic Kidney Disease


ASN 2011 Abstract: [TH-PO248]

Mira T. Keddis, MD, Sahil Khanna, MBBS, Larry M. Baddour, MD, Darell S. Pardi, MD, Qi Qian, MD. Nephrology, Mayo Clinic, Rochester, MN; Gastroenterology, Mayo Clinic, Rochester, MN; Infectious Diseases, Mayo Clinic, Rochester, MN.

Author Interview: David P. Calfee, MD, MS

Clinical and Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus among Patients in an Ambulatory Hemodialysis Center.

Patel G, Jenkins SG, Mediavilla JR, Kreiswirth BN, Radbill B, Salgado CD, Calfee DP.
Department of Medicine, Mount Sinai School of Medicine, New York, New York.
Infect Control Hosp Epidemiol. 2011 Sep;32(9):881-8.

Author Interview: Cheng-Chia Lee, MD

Comparable ten-year outcome in hemodialysis patients with hepatitis C virus and hepatitis B virus coinfection and single hepatitis B virus infection.
Lee CC, Li IJ, Chen YC, Cheng JW, Wu HH, Weng CH, Fang JT, Tian YC.
Department of Nephrology, Lin-Kou Chang Gung Memorial Hospital, Taipei, and Department of Medicine, Chang Gung University, Taiwan, ROC.
Blood Purif. 2011;32(2):89-95.

Author Interview: Dr. Simone Scheithauer:
Improving hand hygiene compliance rates in the hemodialysis setting: more
than just more hand rubs

Nephrol. Dial. Transplant. (2011) doi: 10.1093/ndt/gfr365
Simone Scheithauer Frank Eitner, Jennifer Mankartz , Helga Haefner ,Katharina Nowicki, Jürgen Floege, Sebastian W.  Lemmen
Author Interview : Lorien Dalrymple, MD MPH
Risk of Cardiovascular Events after Infection-Related Hospitalizations in Older Patients on Dialysis.

Dalrymple LS, Mohammed SM, Mu Y, Johansen KL, Chertow GM, Grimes B, Kaysen GA, Nguyen DV.
Clin J Am Soc Nephrol. 2011 May 12
Author Interview: Dr. Steve Wilson
Use of Electrolytically-Produced Sodium Hypochlorite Reduces Infections in Dialysis Facilities


Steve Wilson; Amy Young
DaVita Inc., Denver, CO
National Kidney Foundation Spring Meeting April  Las Vegas NV
Author Interview: Dr. Charmaine Lok Long-term Follow-up of the Hemodialysis Infection Prevention With Polysporin Ointment (HIPPO) Study: A Quality Improvement Report.

Am J Kidney Dis. 2011 Mar;57(3):432-41.
Battistella M, Bhola C, Lok CE.
University Health Network-Toronto General Hospital, Toronto, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada.
High prevalence of mupirocin-resistant staphylococci in a dialysis unit where mupirocin and chlorhexidine are routinely used for prevention of catheter-related infections

J Med Microbiol (2011), DOI: 10.1099/jmm.0.024539-0
Boon Wee Teo, Selwyn J Low, Ying Ding, Tse Hsien Koh  and Li-Yang Hsu
National University Health System; Singapore General Hospital; National University of Singapore

Nasal Carriage of Methicillin-resistant Staphylococcus aureus Is Associated with Higher All-Cause Mortality in Hemodialysis Patients.

Clin J Am Soc Nephrol. 2011 Jan;6(1):167-74.

Lai CF, Liao CH, Pai MF, Chu FY, Hsu SP, Chen HY, Yang JY, Chiu YL, Peng YS, Chang SC, Hung KY, Tsai TJ, Wu KD.
Department of Internal Medicine, Far Eastern Memorial Hospital, No. 21, Nan-Ya South Road, Ban Ciao City, Taipei, 220, Taiwan

Diagnosis and treatment of infective endocarditis in chronic hemodialysis patients.

Chin Med Sci J. 2010 Sep;25(3):135-9.

Tao JL, Ma J, et al
Department of Nephrology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.

Hemodialysis Vascular Access Type and Bloodstream Infection Rates

Eduardo K. Lacson, Weiling Wang, J. Michael Lazarus, Raymond M. Hakim. Fresenius Medical Care, North America, Waltham, MA
November 19, 2010  

Introduction: We evaluated bloodstream infection (BSI) rates based on positive blood cultures by type of vascular access in a national cohort of incident hemodialysis (HD) patients during their first year.

THE IMPACT OF TREATMENT MODALITY ON INFECTION-RELATED HOSPITALIZATION RATES IN PERITONEAL DIALYSIS AND HEMODIALYSIS PATIENTS.

Perit Dial Int. 2010 Jul 29.
Williams VR et al
Infection Prevention and Control, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

Antibiotic lock solutions for the prevention of catheter-related bacteraemia in haemodialysis patients.

Hong Kong Med J. 2010 Aug;16(4):269-74.
Chow KM,
Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong.

Infection-Related Hospitalizations in Older Patients With ESRD.

Am J Kidney Dis. 2010 Jul 7.

Dalrymple LS, et al
Medicine, University of California Davis, Sacramento, CA.

Beat Those Bugs! Implementing contact precautions in community dialysis units for closer-to-home care.

Can J Infect Control. 2010 Spring;25(1):9-16Curtin J, Dalziel C.
Infection Prevention and Control (IPAC), Providence Health Care
Vancouver, BC V6Z 2K5.

A protocolized approach to vancomycin dosing in conventional hemodialysis.
J Nephrol. 2010 May 12.
Panais R, et al
Department of Medicine, Dalhousie University, Halifax, Nova Scotia - Canada.

 

 

 


 
 
 
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